Determination of Serum Immunological Parameters in Children with Recurrent Acute Tonsillitis after Tonsillectomy

Hanan Selman Hessan and Ahmed Mohammed Abbas 563 Abstract Immune status was examined after tonsillectomy operations in 30 children with recurrent acute tonsillitis, their ages ranged between 3-10 years, were clinically diagnosed by ENT surgeon at AlHilla General Teaching Hospital and 10 apparently healthy children were included as a control in the study which lasted from February to May 2011 .Immunological parameters test were done directly postoperative by taking venous blood from the patients and control to determine the immunoglobulins of IgM, IgG, IgA, complement proteins C3 and C4 level in addition to Creactive protein test were done as indicators of inflammation. It was shown that the immunological assays after tonsillectomy revealed positive changes: a significant increases in IgM and IgA levels in serum of patients in comparison to control although were still in normal reference values but serum IgG level and complement proteins C3 and C4 level were normal in addition to the results of CRP in patients giving positive results in comparison to controls. ةصلاخلا صحف مت ىدل ةيعانملا ةلاحلا 23 لافط " باصم "ا نيتزوملا باهتلاب داحلا رركتملا نيتزوملا لاصئتسا ةيممع ءا رجإ دعب تحوا رت مهرامعأ نيب 2 03 و تاونس نيذلا اوصخش ايريرس " لبق نم ءابطأ صاصتخا ةحا رجب فنلأا نذلأاو يف ةرجنحلاو يميمعتلا ةمحلا ىفشتسم و ماعلا 03 لافطأ أ ءاحص ةطباض ةنيعك مل نا ريزح ىلا طابش نم ةرتفمل تدتما يتلا ةسا رد 1300 . رابتخا ريياعملا ةيعانملا دق تيرجأ ةرشابم لاصئتسلاا ةيممع دعب كلذو ىضرملا نم يديرولا مدلا بحسب لافطلأاو ءاحصلأا ديدحتل وتسم ى ةيعانملا تانيلويبومكلا IgM و IgG و IgA ةممتملا تانيتوربو C3 و C4 ةفاضلإاب ىلإ ءا رجإ صحف لا نيتوربلا يمعافت CRP تاباهتللاا ىمع ةلادك . دقو ترهظأ نيتزوملا لاصئتسا ةيممع دعب ةيعانملا تاصوحفلا ةيباجيا تا ريغت ذإ هظ تر ةدايز وتسم يف ةيونعم ى IgM و IgA يف لصم ىضرملا ةنراقم لأاب حص ءا نم مغرلا ىمع اهنأ ةيعيبطلا ةيعجرملا ميقلا نمض عقت نكل ىوتسم IgG و ةممتملا تانيتورب C3 و C4 ةيعيبط تناك يف ىلإ ةفاضإ لصملا نإ ن جئات لا نيتوربلا صحف يمعافت CRP ةيباجيا اهمك تناك ىضرملا يف ب ةنراقم لأا .ءاحص ـــــــــــ ـــــــــــــــــ ـــــــــــــــــــــــ ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ ــــــ ــــــــــــــ ـــــــــــــــــ ـــــــــــــــــ ـــــــــــــــــ ـــــــــــــــــــــــــ ـــــــــــ ـــــــــــــــــ ـــــــ ــــــــــــــــــ ـــــــــــــــــــــــــ ـــــــــــ ـــــــــــــــــ ـــــــــــــــــ ـــــــــــــــــ ـــــــــــــــــ ـــ ــــــ ــــــــــ ـــــــــــــــــ ــــــــــ ــ ـــ Introduction he tonsils are two small glands found at the back of throat behind the tongue. It is thought that they act as a barrier against infection in children whose immune system is still developing [1]. Adenoids and tonsils are anatomically located at the entrance of the respiratory and digestive tracts and in fact are the body’s first line of contact with various pathogens present in food and air [2]. The tonsils are part of secondary lymphatic system in which B lymphocytes are predominant and the most important components of the immune system therefore the cellular and humoral responses depended upon their activities [3]. Tonsillitis is an inflammatory condition of the tonsils due to infection by bacteria, viruses, allergies and respiratory problems. Tonsillitis usually begins with a sudden T M J B Determination of Serum Immunological Parameters in Children with Recurrent Acute Tonsillitis after Tonsillectomy